“Enough is enough.” That’s the message that more than 5,000 Texas A&M University (TAMU) faculty and staff heard on their phones. And the voice at the other end of the line? Well, that likely came as a surprise. It was Hollywood icon Lily Tomlin, who made a very personal plea for their support in urging TAMU President Michael K. Young to end the school’s muscular dystrophy (MD) experiments on dogs.

The Grace and Frankie star pointed out that 35 years of these cruel tests have failed to produce a cure or even a treatment to reverse the symptoms of MD.

Video footage obtained by PETA shows crippled dogs intentionally bred to suffer from a canine form of MD who were caged, sometimes alone, in barren metal cells.

PETA’s efforts to end these pointless and cruel experiments have received support from MD patients, scientists—who have criticized the experiments’ inapplicability to humans—and public figures, including Miami Dolphins quarterback and TAMU alumnus Ryan Tannehill as well as commentator Bill Maher, who called the university “dogs’ worst enemy.”

As Tomlin says in her message, “Enough is enough.” Tell TAMU to shut the dog lab down now.